Neuromuscular blockade is one of the cornerstones of general anaesthesia, used both to facilitate endotracheal intubation and to allow surgical manipulation. Show
However, the activity of intermediate-acting neuromuscular blocking agents could persist after patient arousal from anaesthesia. The partial impairment of muscular activity in the postoperative period can contribute to the development of postoperative pulmonary complications through different mechanisms—namely, impaired contraction of ventilatory muscles with atelectasis formation, inability to cough, and impaired swallowing. 2
Residual paralysis: does it influence outcome after ambulatory surgery?.
Pulmonary complications are common in patients undergoing high-risk surgery, are associated with increased morbidity and mortality, and can increase health-care costs. The effects of neuromuscular blocking agent, reversal agents, and neuromuscular blockade monitoring on the development of postoperative pulmonary complications are uncertain and mainly based on registry-based retrospective studies. 4
Dose-dependent association between intermediate-acting neuromuscular-blocking agents and postoperative respiratory complications.
Unfortunately, the quality of evidence in this field is low. To read this article in full you will need to make a payment References
Article InfoPublication HistoryPublished: September 14, 2018 IdentificationDOI: https://doi.org/10.1016/S2213-2600(18)30363-1 Copyright© 2018 Elsevier Ltd. All rights reserved. ScienceDirectAccess this article on ScienceDirectLinked Articles
What is the most common post op complication?Typical discomforts may include: Nausea and vomiting from general anesthesia. Sore throat (caused by the tube placed in the windpipe for breathing during surgery) Soreness, pain, and swelling around the incision site. Restlessness and sleeplessness.
What are the 2 most common complications of surgery?Common general postoperative complications include postoperative fever, atelectasis, wound infection, embolism and deep vein thrombosis (DVT). The highest incidence of postoperative complications is between one and three days after the operation.
Which respiratory condition is a potential complication associated with surgery?Atelectasis, a common respiratory complication, may contribute to pneumonia and acute respiratory failure. Recently, it has been shown that activation of abdominal muscles during the induction of anesthesia contributes to a reduction of lung capacity, leading to a higher degree of atelectasis.
Which factor increases a patient's risk for delayed wound healing?Wound healing can be delayed by systemic factors that bear little or no direct relation to the location of the wound itself. These include age, body type, chronic disease, immunosuppression, nutritional status, radiation therapy, and vascular insufficiencies.
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